Antibiotics

Details Antibiotics Antibiotics

1981-12-03

1985-06-25

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Plural fermentates of different origin

A61K 3500

Patent

active

045253528

ABSTRACT:
A new antibacterially active agent has been isolated from Streptomyces clavuligerus. This new compound which is designated clavulanic acid has the formula (I): ##STR1## In addition to being a broad spectrum antibiotic of medium potency, clavulanic acid and its salts and esters have the ability to enhance the effectiveness of .beta. lactam antibotics against many .beta.-lactamase producing bacteria.

REFERENCES:
patent: 4123540 (1978-10-01), Howarth
patent: 4140764 (1979-02-01), Howarth

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