Antibiotics

Details Antibiotics Antibiotics

1976-09-20

1980-01-01

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Processes of making, purifying or recovering

424117, A61K 3500

Patent

active

041817168

ABSTRACT:
It has been found that an antibiotic can be obtained by the fermentation of certain strains of Streptomyces olivaceus and related organisms and when pure this antibiotic is an extremely potent inhibitor of many .beta.-lactamases. This antibiotic which we designate MM 4550A may be obtained in substantially pure form by the chromatographic purification of the crude antibacterial complex obtained from the culture medium.

REFERENCES:
patent: 3919415 (1975-11-01), Butterworth et al.
patent: 3928569 (1975-12-01), Umezawa et al.
patent: 3950357 (1976-04-01), Kahan et al.
Maeda et al., J. of Antibiotics, Sep. 1977, pp. 770-772.

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