Antibiotic U-58,431

Details Antibiotic U-58,431 Antibiotic U-58,431

1979-09-27

1981-05-12

Chan, Nicky

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

435117, 435253, 424118, C07D31174

Patent

active

042671124

ABSTRACT:
Novel antibiotic U-58,431 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces helicus Dietz and Li sp. n., NRRL 11461. This antibiotic is active against various Gram-positive bacteria, for example, Staphylococcus aureus, Streptococcus hemolyticus, and Streptococcus faecalis. It is also active against various Gram-negative bacteria, for example, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Salmonella schottmuelleri. It has strong activity against Diplococcus pneumoniae. Thus, antibiotic U-58,431 can be used in various environments to eradicate or control such bacteria.

REFERENCES:
patent: 4027014 (1977-05-01), Ezaki et al.

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