Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 3,10-dihydroxy-2-naphthacene carboxamide or derivative doai
Patent
1998-05-05
2000-01-18
Peselev, Elli
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
3,10-dihydroxy-2-naphthacene carboxamide or derivative doai
A61K 3100
Patent
active
060158034
ABSTRACT:
A method is provided for the treatment of age-related macular degeneration by administering various antibiotics, such as tetracycline and its derivatives, rifamycin and its derivatives, macrolides, and metronidazole, to a patient in a therapeutically effective amount.
REFERENCES:
patent: 5207660 (1993-05-01), Lincoff
Bressler et al.: Age-related macular degeneration. Surv. Opthalmol. 32:375-413, 1988.
Penfold et al.: Senile macular degeneration: The involvement of giant cells in the atrophy of the retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 27:364-371, 1986.
Penfold et al.: Age-related macular degeneration: Ultrastructural studies of the relationship of leucocytes to angiogenesis. Graefe's Arch. Ophthalmol. 2256:70-76, 1987.
Tilley et al.: Minocycline in rheumatoid arthritis. A forty-eight week double blind placebo controlled trial. MIRA trial Group. Annals of Internal Medicine 122(2):81-89, 1995.
Brown et al.: Diagnosis and treatment of ocular rosacea. Ophthalmology 85:779-786, 1978.
Salamon: Tetracyclines in ophthalmology. Surv. Ophthalmol. 29:265-275, 1985.
Bressler et al.: The grading and prevalence of macular degeneration in Chesapeake by Waterman. Arch. Ophthalmol. 107:847-852, 1989.
Smiddy et al.: Prognosis of patients with bilateral macular drusen. Ophthalmology 91:271-276, 1984.
Friedman et al.: Ocular blood flow velocity in age-related macular degeneration. Ophthalmology 102(4):640-646, 1995.
Hardy: Retina & Intraocular Tumors, in Vaughan et al. (ed): General Ophthalmology (4th ed), Appleton & Lange, Connecticut, 1995, pp. 186-188.
Fingeret et al.: Interferometry, in Atlas of primary eyecare procedures, Appleton & Lange, Connecticut, 1990, pp. 272-273.
Ratzenhofer et al., "In-vitro inhibition of collagenase activity in epidermolysis bullosa hereditaria dystrophica", Z Hautkr, Dec. 15, 1978, 53(24):929-34, [English abstract].
Miyachi et al., "Effect of antibiotics on the generation of reactive oxygen species", J. Invest. Dermatol., Apr., 1986, 86(4):449-53.
Umeki, "Anti-inflammatory action of erythromycin: Its inhibitory effect on neutrophil NADPH oxidase activity", Chest, Oct., 1993, 104(4):1191-3.
LandOfFree
Antibiotic treatment of age-related macular degeneration does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibiotic treatment of age-related macular degeneration, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibiotic treatment of age-related macular degeneration will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-563509