Antibiotic treated implantable medical devices

Details Antibiotic treated implantable medical devices Antibiotic treated implantable medical devices

2006-07-25

2006-07-25

McDermott, Corrine (Department: 3738)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Heart valve

Annular member for supporting artificial heart valve

Reexamination Certificate

active

07081133

ABSTRACT:
Pannus-resisting implantable medical devices comprise one or more antimicrobial reservoirs, each such reservoir incorporating antimicrobial substances in predetermined distributions for timed release in vivo. Predetermined distributions of antimicrobial substances incorporated in antimicrobial reservoirs are achieved through use of fluid solvent carriers, which may comprise supercritical fluid solvents. Precipitation of antimicrobial substances from such solvent carriers in predetermined distributions is accomplished through evaporation and/or application of heating, cooling or decreased ambient pressure to the solvent carriers.

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patent: 6585767 (2003-07-01), Holley et al.
patent: WO00/54745 (2000-09-01), None
Irwin et al., “Long Term Evaluation of Prosthetic Mitral Valves in Sheep,”J. Invest. Surgery6:133-141 (1993).

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