Antibiotic TAN-420

Details Antibiotic TAN-420 Antibiotic TAN-420

1983-12-02

1985-09-10

Bond, Robert T.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

435128, 435872, C07D22506, C12P 1300, C12R 1365

Patent

active

045405174

ABSTRACT:
A compound of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and each represents hydrogen or methyl and X is ##STR2## provided that when R.sub.1 is hydrogen, R.sub.2 is hydrogen or methyl and X is ##STR3## and when R.sub.1 is methyl, R.sub.2 is methyl and X is ##STR4## is produced by cultivating a a microorganism belonging to the genus Streptomyces in a culture medium. Said compound is useful as an antimicrobial agent and so forth.

REFERENCES:
patent: 4187292 (1980-02-01), Higashide et al.
patent: 4421687 (1983-12-01), Hasegawa et al.
patent: 4421688 (1983-12-01), Muroi et al.
Chemical Abstracts, vol. 97, (1982) Item 106668(s) Abstracting Hatano et al., "Agrio. Biol. Chem." (1982), vol. 46, No. 6, pp. 1699-1702.
Chemical Abstracts, vol. 98, (198) Item 83315(d) Abstracting Ono et al., "Gann" (1982), vol. 73, No. 6, pp. 938-944.
Muroi et al., Tetrahedron Letters, vol. 21, pp. 309-312 (1980).
Muroi et al., Tetrahedron, vol. 37, pp. 1123-1130 (1981).
Sasaki et al., Journal of the American Chemical Society, vol. 92, pp. 7591-7593 (1970).
Johnson et al., Journal of the American Chemical Society, vol. 96, pp. 3316-3317 (1974).
Omura et al., Tetrahedron Letters, No. 44, pp. 4323-4326 (1979).
Iwai et al., The Journal of Antibiotics, vol. 33, pp. 1114-1119 (1980).

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