Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2005-07-05
2005-07-05
Azpuru, Carlos A. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
C424S426000, C523S114000, C523S115000
Reexamination Certificate
active
06913764
ABSTRACT:
The present invention concerns an antibiotic/antibiotics preparation for resorbable and non-resorbable implants for human and veterinary medicine, for the treatment of local microbial infections in hard and soft tissue. The invented antibiotic/antibiotics preparation is a mixture consisting of at least one amphiphilic component of a representative of the alkyl sulfates, aryl sulfates, alkylaryl sulfates, cycloalkyl sulfates, alkylcycloalkyl sulfates, alkyl sulfamates, cycloalkyl sulfamates, alkylcycloalkyl sulfamates, aryl sulfamates, alkylaryl sulfamates, alkyl sulfonates, fatty acid-2-sulfonates, aryl sulfonates, alkylaryl sulfonates, cycloalkyl sulfonates, alkylcycloalkyl sulfonates, alkyl disulfates, cycloalkyl disulfates, alkyl disulfonates, cycloalkyl disulfonates, aryl disulfonates, alkylaryl disulfonates, aryl trisulfonates and alkylaryl trisulfonates as well as at least one antibiotic component from the group of aminoglycoside antibiotics, lincosamide antibiotics, 4-quinolone antibiotics and tetracycline antibiotics, and if need be at least one anhydrous organic auxiliary component and if need be at least one inorganic auxiliary component and if need be at least one biologically active component. The antibiotic/antibiotics preparation of the invention has a retarding active ingredient release.
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Kühn Klaus-Dieter
Schnabelrauch Matthias
Vogt Sebastian
Azpuru Carlos A.
Heraeus Kulzer GmbH & Co. KG
Norris McLaughlin & Marcus PA
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