Antibiotic reuterin

Details Antibiotic reuterin Antibiotic reuterin

1993-07-27

1995-05-09

Marx, Irene

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

435184, 435124, C12N 902, C12N 999

Patent

active

054139600

ABSTRACT:
The antibiotic .beta.-hydroxypropionaldehyde is obtained by cultivating strains of Lactobacillus reuteri under anaerobic conditions in the presence of glycerol or glyceraldehyde. This antibiotic has activity against Gram positive and Gram negative bacteria, against the yeast, Saccharomyces cerevisiae, and against the protozoan, Trypanosoma cruzi, and decreases ribonucleotide reductase activity.

REFERENCES:
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Merck Index, Tenth Ed., 1983, p. 5138.
Neilsen, A. et al., .sup.13 C and .sup.1 H NMR Study of Formaldehyde Reactions with Acetaldehyde and Acrolein, Pol. J. Chem., 55:1393-1403, 1981.
Reed, G., Starter Cultures for Fermented Diary Products, in Biotechnology, vol. 5, 1983.
Sandine, W. E. et al., Lactic Acid Bacteria in Food and Health: A Review with Special Reference to Enteropathogenic Escherichia coli as Well as Certain Enteric Diseases and Their Treatment with Antibiotics and Lactobacilli, J. Milk Food Technol., 5:691-702, 1972.
Sarra, P. G. et al., Study on Crop Adhesion Determinant in Lactobacillus reuteri, Microbiologica, 9:279-285, 1986.
Shahani, K. M. et al., Natural Antibiotic Activity of Lactobacillus acidophilus and Bulgaricus, Cult. Dairy Prod. J., 12:8-11, 1977.
Sobolov, et al., Metabolism of Glycerol by an Acrolein-Forming Lactobacillus, J. Bacteriol., 79:261-266, 1960.
Thelander, L. et al., Ribonucleoside Diphosphate Reductase (Escherichia coli), Methods Enzymol., vol. LI, pp. 227-237, 1978.
Vescovo, M. et al., Drug Resistance Plasmids in Lactobacillus acidophilus and Lactobacillus reuteri, Appl. Environ. Microbiol., 43:50-56, 1982.

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