Antibiotic producing Streptomyces thiolactonus

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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435129, 435886, C12N 120, C12P 1302, C12R 1465

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active

046893008

ABSTRACT:
Novel antibiotic U-68,204 is produced in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces thiolactonus, NRRL 15439. This antibiotic is active against various Gram-positive bacteria. Thus, antibiotic U-68,204 can be used in various environments to eradicate or control such bacteria.

REFERENCES:
Sasaki, H. et al.; `Thiolactomycin, A New Antibiotic, II Structure Elucidation`; J. Antibiotics, vol. 35, No. 4, pp. 396-400; Apr. 1982.
Omura, S. et al.; `Thiotetromycin, A New Antibiotic, Taxonomy, Production, Isolation and Physiochemical and Biological Properties`; J. Antibiotics, vol. 36, No. 2, pp. 109-114, Feb. 1983.
Shizuri, Y. et al.; `Isolation and Structure of Citreothiolactone, a Novel Metabolite of Penicillium Citreo-Viride B.`; Tetrahedron Letters, vol. 24, No. 10, pp. 1053-1054; 1983.

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