Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis
Patent
1975-08-21
1976-11-30
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
Having a known elemental analysis
195 80R, A61K 3574
Patent
active
039950280
ABSTRACT:
The present invention relates to a new antibiotic designated as OS-3256-B. OS-3256-B exhibits excellent inhibitory activities against animal tumors such as leukemia L-1210, Sarcoma-180 and Hela cells and gram-positive bacteria and is classified into the diazocompounds group. However, chromatographic analysis, Rf value and other experimental data reveal that OS-3256-B is a new compound of the type of azaamino acid derivatives. The present invention also provides a process for producing OS-3256-B by fermentation, in which OS-3256-B is produced by culturing a microorganism belonging to Streptomyces candidus var. azaticus in a culture medium conventionally used for culturing Streptomyces strain microorganisms.
REFERENCES:
derwent Farmpol No. 70217v 40, Abstracting JA 095234, Published May 15, 1974.
Awaya Juichi
Komiyama Kanki
Oiwa Ruiko
Omura Satoshi
Satoh Keiki
Goldberg Jerome D.
The Kitasato Institute
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