Antibiotic oil suspensions

Details Antibiotic oil suspensions Antibiotic oil suspensions

1996-12-09

1998-04-07

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

514206, A61F 202, A61K 31545

Patent

active

057361517

ABSTRACT:
The present invention provides for the inclusion of small amounts of water in oil suspensions of active drugs, such as ceftiofur hydrochloride of formula I. The resulting suspensions have improved resuspendability. Improved resuspendability results in an improved product because less shaking of the suspension is required before dosing. ##STR1##

REFERENCES:
patent: 4464367 (1984-08-01), Labeeuw
patent: 4877782 (1989-10-01), Cazers et al.
patent: 4902683 (1990-02-01), Amin
patent: 4937330 (1990-06-01), Sacks
patent: 5134137 (1992-07-01), Cazers et al.
patent: 5223496 (1993-06-01), Cazers et al.
Amin, M.I., et al., J. Pharm. Sci., vol. 76(11):S255 (1976).
Evans, R.A., et al., "Certiofur Hydrochloride, A New Broad-Spectrum Cephalosporin: Effectiveness Against Induced Haemophilus Pleuropneumoniae of Growing Swine," Proceedings of the International Pig Veterinary Society, 10th Congress, Rio de Janeiro, Brazil, p. 94 (1988).
Evans, R.A., et al., "Effectiveness of Ceftiofur Hydrochloride, A New Broad-Spectrum Cephalosporin, in Treatment of Colibacillosis in Neonatal Swine," Proceedings of the International Pig Veterinary Society, 10th Congress, Rio de Janeiro, Brazil, p. 108 (1988).

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