Antibiotic NK86-0279, process for production of the same and app

Details Antibiotic NK86-0279, process for production of the same and app Antibiotic NK86-0279, process for production of the same and app

1988-12-22

1991-03-26

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435886, 435 76, 4352535, 536 168, 536 14, 536 181, 514 27, C12P 106, A61K 3170, A61K 3171

Patent

active

050030566

ABSTRACT:
This invention relates to an antibiotic NK86-0279 of the formula: ##STR1## which exhibits antifungal, antitumor, vascularizations-inhibitory and insecticidal activities.

REFERENCES:
patent: 4459291 (1984-07-01), Shirahata et al.
patent: 4511560 (1985-04-01), Tomita et al.
patent: 4626503 (1986-12-01), Lee et al.
Chem. Abs., vol. 107, 1987, p. 333, Abs. No. 112298n, "Oligomycin E, a New Antitumor Antibiotic Produced by Streptomyces sp. MCI-2225", & J. Antibiot. 1987, 40(7), 1053-7 (Abstract).
Chem. Abs., vol. 96, 1982, p. 292, Abs. No. 65333n, "Trioxacarcins, Novel Antitumor Antibiotics, I. Producing Organism, Fermentation and Biological Activities", & J. Antibiot. 1981, 34(12), 1519-24 (Abstract).
Chem. Abs., vol. 88, 1978, p. 180, Abs. No. 59931z, "Biological Properties of Culture 6734-21 and Conditions for the Isolation of the Antiviral Antibiotic Produced by It", & Antibiotiki (Moscow) 1977, 22(12), 1063-5 (Abstract).
Chem. Abs., vol. 99, 1983, p. 491, Abs. No. 15683g, & JP-A-58 65 293 (Kyowa Hakko Kogyo Co., Ltd.) 18-04-1983.
EP-A-O 058 518 (Merck) (Whole document).
Chem. Abs., vol. 96, 1982, p. 292, Abs. No. 65334p, "Trioxacarcins, Novel Antitumor Antibiotics. II. Isolation, Physicochemical Properties and Mode of Action", & J. Antibiol. 1981, 34(12), 1525-30.
The Journal of Antibiotics, vol. XL, No. 7, pp. 1053-1057.

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