Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis
Patent
1976-09-20
1980-11-25
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
Having a known elemental analysis
26032627, 26034631, 124274, 424114, A61K 3500
Patent
active
042358825
ABSTRACT:
It has been found that an antibiotic can be obtained by the fermentation of certain strains of Streptomyces olivaceus and related organisms and when pure this antibiotic is an extremely potent inhibitor of many .beta.-lactamases. This antibiotic which we designate MM 4550A may be obtained in substantially pure form by the chromatographic purification of the crude antibacterial complex obtained from the culture medium.
REFERENCES:
patent: 3919415 (1975-11-01), Butterworth et al.
patent: 3928569 (1975-12-01), Umezawa et al.
patent: 3950357 (1976-04-01), Kattan et al.
Maeda et al., J. of Antibiotics, Sep. 1977, pp. 770-772.
Butterworth Dennis
Cole Martin
Hood John D.
Beecham Group Limited
Goldberg Jerome D.
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