Antibiotic KA-7038 and compositions containing same

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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424180, 536 17R, A61K 3171, C07H 1522

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active

043128580

ABSTRACT:
An antibiotic substance KA-7038 selected from the group consisting of the compounds having formulae I to VII described in claim 1, mixtures thereof and acid addition salts thereof; an antibiotic composition composed of (i) antibiotically effective amount of aforesaid antibiotic substance KA-7038, and (ii) a pharmaceutically acceptable diluent or carrier. The antibiotic substance KA-7038 can be produced by cultivating an antibiotic substance KA-7038-producing strain belonging to genus Streptomyces, for example Streptomyces sp. KC-7038, and isolating the antibiotic substance KA-7038 from the culture broth.

REFERENCES:
patent: 3931400 (1976-01-01), Nara et al.
patent: 3976768 (1976-08-01), Nara et al.
patent: 4145253 (1979-03-01), Iida et al.
patent: 4169198 (1979-09-01), Martin et al.
patent: 4176178 (1979-11-01), Martin et al.
patent: 4209612 (1980-06-01), Takahashi et al.
Egan, et al. "The Jour. of Antibiotics", vol. XXX, No. 7, pp. 552-563, Jul. 1977.

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