Antibiotic from Streptomyces clavulicerus

Details Antibiotic from Streptomyces clavulicerus Antibiotic from Streptomyces clavulicerus

1981-09-24

1985-07-16

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514210, A61K 3142

Patent

active

045297207

ABSTRACT:
A new antibacterially active agent has been isolated from Streptomyces clavuligerus. This new compound which is designated clavulonic acid has the formula (I): ##STR1## In addition to being a broad spectrum antibiotic of medium potancy, clavulanic acid and its salts and esters have the ability to enhance the effectiveness of .beta. lactam antibiotics against many .beta.-lactamase producing bacteria.

REFERENCES:
Derwent Farmdoc #72840 w/44 Abstracting DT 2517316, published 10-23-1975.

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