Antibiotic formulation and use for drug resistant infections

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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264 41, 264 43, A61K 9127, A61K 9133

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active

057561214

ABSTRACT:
A liposomal aminoglycoside formulation comprising a neutral lipid, a negatively charged lipids and a sterol. The formulation contains unilamellar vesicles having an average size below 100 nm. A process of making liposomes containing an aminoglycoside is provided where the hydration temperature is significantly below the transition temperature of the formulation. A method for the treatment of drug susceptible and drug resistant bacteria.

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