Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1995-06-06
1998-05-26
Kishore, Gollamudi S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
A61K 9127, A61K 9133
Patent
active
057561206
ABSTRACT:
A liposomal aminoglycoside formulation comprising a neutral lipid, a negatively charged lipids and a sterol. The formulation contains unilamellar vesicles having an average size below 100 nm. A process of making liposomes containing an aminoglycoside is provided where the hydration temperature is significantly below the transition temperature of the formulation. A method for the treatment of drug susceptible and drug resistant bacteria.
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Bracken Kevin R.
Chiang Su-Ming
Hersch Evan M.
Petersen Eskild A.
Proffitt Richard T.
Kishore Gollamudi S.
NeXstar Pharmaceuticals, Inc.
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