Antibiotic formulation and use for bacterial infections

Details Antibiotic formulation and use for bacterial infections Antibiotic formulation and use for bacterial infections

1998-05-21

1999-09-28

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

264 43, A61K 9127, A61K 9133

Patent

active

059584491

ABSTRACT:
A liposomal aminoglycoside formulation comprising a neutral lipid, a negatively charged lipid and a sterol. The formulation contains unilamellar vesicles having an average size below 100 nm. A process of making liposomes containing an aminoglycoside is provided. A method is also provide for the treatment of drug susceptible and drug resistant bacteria.

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