Antibiotic derivatives, derived from cephalosporins with thiazol

Details Antibiotic derivatives, derived from cephalosporins with thiazol Antibiotic derivatives, derived from cephalosporins with thiazol

1982-03-02

1984-10-09

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 22, 544 27, A61K 31545, C07D50156

Patent

active

044761236

ABSTRACT:
The present invention relates to derivatives of the family of cephalosporins, of formula: ##STR1## in which ##STR2## is an acid, a salt or an ester of this acid, R.sub.1 is a group of form ##STR3## in which R.sub.A and R.sub.B are H or alkyl or form a saturated cyclobutyl or cyclopentyl ring and R.sub.C is H or COOH, R.sub.2 is a thiazolium salt or a OCOCH.sub.2 R.sub.D group in which R.sub.D is a 1,3-thiazol-4-yl group.
The invention also relates to a process for preparing the products of formula (I) and to drugs containing said products.

REFERENCES:
patent: 4237128 (1980-12-01), Cimarusti et al.
patent: 4399131 (1983-08-01), Durckheimer et al.

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