Antibiotic derivatives

Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis

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A61K 3500

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active

039490793

ABSTRACT:
A process for producing the antibiotic pleuromutilin by cultivating strains of Clitopilus passeckerianus (Pil.) Sing in an aqueous nutrient medium. The production of esters of pleuromutilin and hydrogenation products thereof are also described. The pleuromutilin and derivatives thereof are useful as an antibacterial ingredient in animal feed compositions.

REFERENCES:
patent: 2903356 (1959-09-01), Lampen et al.
Kavanagh et al., Proc. Nat. Acad. Sci., Vol. 37, 1951, pp. 570-574.
Szybalski; W., Applied Microbiology, Vol. 2, 1954, pp. 57-63.

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