Antibiotic cytophagin and a process for producing the same

Details Antibiotic cytophagin and a process for producing the same Antibiotic cytophagin and a process for producing the same

1981-07-01

1983-07-12

Tanenholtz, Alvin E.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

435170, 435 68, 435822, A61K 3500, C12P 104, C12P 2100, C12R 101

Patent

active

043930476

ABSTRACT:
A substance having antibiotic activity, designated as cytophagin, which is stable in the form of colorless powder and which has an elemental analysis of H: 6.94%, C: 47.22% and N: 13.21%, a molecular weight of 1,000 to 1500. This substance is believed to be composed of 11 amino acids and exhibits a strong activity against Gram-positive bacteria. Cytophagin is produced by fermentation using a microorganism belonging to the genus Cytophaga and capable of producing cytophagin. A preferred strain is Cytophaga BMF 694-N3 (FERM P-4846;NRRL B-12109). Cytophagin is of potential interest as medicament or veterinary agent because of its antibiotic activity.

REFERENCES:
Lewin et al., J. Gen. Microbiol., vol 58, pp. 145-170 (1969).

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