Antibiotic compounds for ruminant feed utilization improvement

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Lipid or oil

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424115, A61K 3135

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active

039378365

ABSTRACT:
Antibiotics of the group A204, X537A, dianemycin, monensin, nigericin, and X206, the deshydroxymethyl derivatives of monesin and nigericin, and their physiologically acceptable salts and esters, improve the digestive efficiency of certain herbivorous animals. Oral administration of the antibiotics to ruminant animals having a developed rumen function, and to animals which ferment fibrous vegetable matter in the cecum, changes the digestive fermentation to produce more propionates relative to the production of acetates, thereby improving feed utilization.

REFERENCES:
patent: 3555150 (1971-01-01), Gorman et al.
patent: 3577531 (1971-05-01), Gorman et al.
patent: 3744732 (1974-02-01), Raun
patent: 3839557 (1974-10-01), Raun
J. Am. Chem. Soc. (1951) 73:5295-5298.
Stedman's Medical Dictionary (1961) p. 331.
O'Conner et al., J. Anim. Sci., 30, 812-818 (1970).
Purser et al., J. Anim. Sci, 24, 1039-1044 (1965).

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