Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1981-04-03
1982-07-27
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125R, 424119, A61K 3700, C07C10352, A61K 3500
Patent
active
043417680
ABSTRACT:
A novel peptide antibiotic complex designated herein as Bu-2470 is produced by fermentation of Bacillus circulans strain G493-B6 (ATCC 31,805). Complex Bu-2470 may be separated into four bioactive peptide antibiotics designated as Bu-2470A, B.sub.1, B.sub.2a, and B.sub.2b. The complex and individual bioactive factors possess significant antimicrobial activity.
REFERENCES:
patent: 3856938 (1974-12-01), Murao et al.
patent: 3880944 (1975-04-01), Kawaguchi et al.
Biol. Abstr. (67) 59991; 59994; 59995, (63) 19114 and (69) 71255.
The Journal of Antibiotics 29, (1976), 516-519 and 1339-1340 and 1241-1242.
Journal of Chromatography 97 (1974), 112-114.
The Journal of Antibiotics (1973), 444-448, vol. 26.
The Journal of Antibiotics (28), 379-389, (1975).
Japanese Abstract (1974), 160491.
Kawaguchi Hiroshi
Konishi Masataka
Miyaki Takeo
Tsukiura Hiroshi
Bristol-Myers Company
Morse David M.
Phillips Delbert R.
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