Antibiotic compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S183000

Reexamination Certificate

active

07745644

ABSTRACT:
Fermentation of a nutrient medium with a eubacteriumStreptomycessp. yields a novel antibacterial compound of structure (I).

REFERENCES:
patent: 6365610 (2002-04-01), Sasaki et al.
Karsi, A., Gülsoy, N., Corb, E., Dumpala, P.R., Lawrence, M.L. (2009) High-Throughput Bioluminescence-Based Mutant Screening Strategy for Identification of Bacterial Virulence Genes. Applied and Environmental Microbiology, vol. 75, No. 7, pp. 2166-2175.
Hensel, M., Holden, D.W. (1996) Molecular genetic approaches for the study of virulence in both pathogenic bacteria and fungi. Microbiology, vol. 142, pp. 1049-1058.
Kanbe, K., Mimura, Y., Tamamura, T., Yatagai, S., Sato, Y., Takahashi, A., Sato, K. (1992) AB3217-A, A Novel Anti-Mite Substance Produced by a Strain ofStreptomyces platensis. The Journal of Antibiotics, vol. 45, No. 4, pp. 458-464.
Singh, S.B. and coworkers. (2006) Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy. The Journal of the American Chemical Scoiety, vol. 128, pp. 11916-11920.
F. D. Lowry et al., “Antimicrobial Resistance: the example ofStaphylococcus aureus”, 2003, pp. 1265-1273, vol. 111, No. 9, J. of Clinical Investigation.
E. B. Shirling et al., “Methods for Characterization ofStreptomycesSpecies”, 1966, pp. 313-340, vol. 16, No. 3, International Journal of Systematic Bacteriology.

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