Antibiotic compound

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...

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Details

2601125R, A61K 3700, C07C10352

Patent

active

044092105

ABSTRACT:
A novel water-soluble peptide designated herein as Bu-2517 is produced by fermentation of Empedobacter sp. strain G393-B445 (ATCC 31962). The antibiotic exists in a cyclic depsipeptide structure and contains the amino acids D-serine, D-proline, L-proline, D-threo-.beta.-hydroxyaspartic acid, L-threo-.beta.-hydroxyaspartic acid, L-arginine and trans-L-3-hydroxyproline and the residue of the C.sub.14 fatty acid, 3-hydroxytetradecanoic acid. The Bu-2517 antibiotic inhibits the growth of a variety of aerobic and anaerobic gram-positive bacteria.

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