Antibiotic compositions

Details Antibiotic compositions Antibiotic compositions

1981-03-09

1983-04-12

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Plural fermentates of different origin

A61K 3500

Patent

active

043797814

ABSTRACT:
Macrolide antibiotics tylosin, spiromycin, cleandomycin, magnamycin, and leucomycin in combination with aminoglycoside antibiotics tobramycin, apramycin, nebramycin 5, gentamicin and neomycin form synergistic compositions which inhibit the growth of mycoplasma in mammalian tissue cultures. Tylosin-apramycin compositions enhance the feed efficiency and weight gain in post weaned pigs and are useful in the control of Pasturella hemolytica an infectious organism in cattle.

REFERENCES:
patent: 3178341 (1965-04-01), Hamill et al.
patent: 3491187 (1970-01-01), Ely
patent: 3691279 (1972-09-01), Thompson et al.
Associated Biomedio Systems, Inc., Catalogue, p. 10.
Chemical Abstracts 84:84801 G (1976).
The Merck Index, 9th Ed. (1976), pp. 230, 565, 714, 887, 1131, 1260 and 1261.
Schering Diagnostics, "Gentamycin" Advertising Literature.
Micro Biological Assoc., Inc., Advertising Literature Titled "The Ideal Antibiotic" and Gentamicin.
French Republic Search Report.
N. Shishkov and D. Droumev, "Possibilities for Synergic Action of Some Drug Combinations Against Mycoplasma Gallisepticum," Proc. Int. Congr. Chemother., 8th 1973 (Publ. 1974) 1, 356-361 (Eng.) Ed. by Daikos, G. K., Hell. Soc. Chemother.: Athens, Greece.

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