Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis
Patent
1977-09-09
1978-09-05
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
Having a known elemental analysis
195 80R, A61K 3500
Patent
active
041120710
ABSTRACT:
A novel anthracycline antibiotic complex designated herein as figaroic acid complex is produced by fermentation of Streptosporangium sp. strain C-31,751, A.T.C.C. 31129. Figaroic acid complex inhibits the growth of various microorganisms, e.g., Staphylococcus aureus, exhibits phage inducing properties and inhibits the growth of various tumors in rodents, e.g., Sarcoma 180, L-1210 lymphatic leukemia, B-16 melanoma, Walker 256 carcinosarcoma and P-388 lymphatic leukemia.
REFERENCES:
patent: 3590028 (1971-06-01), Arcamone et al.
patent: 3616242 (1971-10-01), Belloc et al.
patent: 3864480 (1975-02-01), Wang et al.
Brazhnikova et al., J. of Antibiotics, Apr. 1974, pp. 254-259.
Bradner William T.
Bush James A.
Nettleton, Jr. Donald E.
Bristol-Myers Company
Goldberg Jerome D.
Morse David M.
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