Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1981-08-28
1983-11-22
Wiseman, Thomas G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
564159, 435129, 435832, A61K 3116, C12P 2100, C12R 107
Patent
active
044168993
ABSTRACT:
A new antibiotic BMG162-aF2 having the formula ##STR1## can be obtained by cultivating a BMG162-aF2-producing strain belonging to the genus Bacillus in a culture medium to produce and accumulate the said BMG162-aF2 and then recovering it from the culture medium. The antibiotic BMG162-aF2 thus obtained or a pharmaceutically acceptable salt thereof can be used for the treatment of a transplanted tumor in warmblooded animals.
REFERENCES:
patent: 4163796 (1979-08-01), Burk
patent: 4226808 (1980-10-01), Nagabhushan
patent: 4328229 (1982-05-01), Fujii et al.
Shoji et al., J. Antibiotics, vol. 29, No. 4, 1976, pp. 390-393.
Kido et al., J. Antibiotics, vol. 33, No. 8, 1980, pp. 791-795.
Iinuma Hironobu
Kunimoto Setsuko
Naganawa Hiroshi
Takeuchi Tomio
Umezawa Hamao
Morse David M.
Pepper Frederick W.
Wiseman Thomas G.
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
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