Antibiotic BMG162-aF2, a process for production thereof, and ant

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing nitrogen-containing organic compound

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435253, 435 68, C12P 1302, C12P 2100, C12N 120

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active

044748809

ABSTRACT:
A new antibiotic BMG162-aF2 having the formula ##STR1## can be obtained by cultivating a BMG162-aF2-producing strain belonging to the genus Bacillus in a culture medium to produce and accumulate the said BMG162-aF2 and then recovering it from the culture medium. The antibiotic BMG162-aF2 thus obtained or a pharmaceutically acceptable salt thereof can be used for the treatment of a transplanted tumor in warmblooded animals.

REFERENCES:
patent: 2998438 (1961-08-01), Charney et al.
patent: 3617448 (1971-11-01), Mann
patent: 3743580 (1973-07-01), Umezawa et al.
Shoji et al., J. Antibiotics, vol. 29, No. 4, 1976, pp. 390-393.
Kido et al., J. Antibiotics, vol. 33, No. 8, 1980, pp. 791-795.

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