Antibiotic and method of production thereof

Details Antibiotic and method of production thereof Antibiotic and method of production thereof

2011-07-12

2011-07-12

Peselev, Elli (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C549S263000

Reexamination Certificate

active

07977375

ABSTRACT:
The invention relates to a novel antibiotic from the macrolactin group and a microbial method for production of macrolactins and a novel isolatedBacillus subtilis, of application as the producing strain for the known Macrolactin A and the novel derivative.

REFERENCES:
patent: 9301970 (1997-11-01), None
International Search Report.
Jaruchoktaweechai, Chutima et al., “New Macrolactins from a MarineBacillussp. Sc026”,Journal of Natural Products, 2000, pp. 984-986. XP-002352574.
Smith, Amos B. et al., “Total Synthesis of (−)-Macrolactin A”,Journal of the American Chemical Society, vol. 118, 1996, pp. 13095-13096. XP-002207324.
Smith, Amos B. et al., “Total Synthesis of (−)-Macrolactin A, (+)-Macrolactin E, and (−)-Macrolactinic Acid: An Exercise in Stille Cross-Coupling Chemistry”,Journal of the American Chemical Society, vol. 120, 1998, pp. 3925-3948. XP-002352575. (Spec, p. 2).
Marino, Joseph P. et al., “Stereocontrolled Synthesis of (−)-Macrolactin A”,Journal of the American Chemical Society, vol. 124, No. 8, 2002, pp. 1664-1668. XP-002352576. (Spec, p. 2).

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