Antibiotic aminoglycosides, processes of preparation and pharmac

Details Antibiotic aminoglycosides, processes of preparation and pharmac Antibiotic aminoglycosides, processes of preparation and pharmac

1975-03-07

1976-09-21

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, C07H 1522

Patent

active

039818616

ABSTRACT:
There are disclosed pharmaceutically-active aminoglycosides comprising 4-0-(2',6'-diamino 2', 3', 4', 6'-tetradesoxy .alpha.,D-erythrohexopyrannosyl) 6-0-(3"-methylamino 3", 4", 6"-tridesoxy .alpha.,D-xylohexopyrannosyl) 2-desoxystreptamine of the formula: ##SPC1##
And the addition salts thereof with mineral acids or organic acids. Also disclosed are methods for preparation of the novel products as well as certain novel intermediate products. There are also disclosed pharmaceutical compositions in which the novel products are the active agents as well as methods for use of compositions as antibiotic agents.

REFERENCES:
patent: 3753973 (1973-08-01), Umezawa et al.
patent: 3878193 (1975-04-01), Reimann
patent: 3925354 (1975-12-01), Umezawa et al.
Mallam et al., "The Jour. of Antibiotics," vol. XXVI, No. 12, pp. 782-783.

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