Antibiotic aminoglycosides, processes of preparation and pharmac

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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536 17, 536 4, C07H 1522, A61K 3171

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active

040312100

ABSTRACT:
There are disclosed pharmaceutically-active aminoglycosides comprising 4-O-[2',6'-diamino 2',3',6'-tridesoxy .alpha.,D-ribohexopyranosyl] 6-O-[3"-methylamino 3",4",6"-tridesoxy .alpha.,D-xylohexopyranosyl] 2-desoxystreptamine of the formula: ##STR1## and the addition salts thereof with mineral acids or organic acids. Also disclosed are methods for preparation of the novel products as well as certain novel intermediate products. There are also disclosed pharmaceutical compositions in which the novel products are the active agents and a method for the treatment of bacteria infections in humans and animals.

REFERENCES:
patent: 3925354 (1975-12-01), Umezawa et al.
patent: 3929762 (1975-12-01), Umezawa et al.

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