Antibiotic alisamycin and its use

Details Antibiotic alisamycin and its use Antibiotic alisamycin and its use

1991-01-10

1992-05-19

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549546, A61K 31335, C07D30314

Patent

active

051149672

ABSTRACT:
Alisamycin, a compound of the formula I ##STR1## has an antibiotic, antitumor and antiparasitic action.

REFERENCES:
patent: 4595770 (1986-06-01), Brodasky et al.
Grote et al., "Metabolic Products of Microorganisms, 244, Colabomycins, New Antibiotics of the Manumycin Group from Streptomyces griseoflavus", J. Antibiotics 41(9): 1178-1195 (1988).
Brodasky et al., "U-56, 407, A New Antibiotic Related to Asukamycin: Isolation and Characterization", J. Antibiotics 36(8): 950-956 (1983).
Slechta et al., "Isolation and Characterization of a New Antibiotic U-62162", J. Antibiotics 35(5): 556-560 (1982).
Zeeck et al., "The Structure of Manumycin", J. Antibiotics 40(11): 1530-1540 (1987).
Kakinuma et al., "The Structure of Asukamycin, a Possible Shunt Metabolite from 3-Dehydroquinic Acid in the Shikimate Pathway", J. Am. Chem. Soc. 101(12): 3402-3404 (1979).
Zeeck, A. et al., J. Antibiotics 41(11): 1541-1548 (1987).
Thiericke, R. et al., J. Antibiotics 41(11): 1549-1554 (1987).
Davis, B. D. et al., Microbiology, 3rd ed., pp. 583, 584, 621, 629, and 842 (1980).

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