Antibiotic agent

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435128, 435147, 435155, C12P 1718, C12P 1300, C12P 724, C12P 702

Patent

active

053668804

ABSTRACT:
A new antibiotic cyclic lipopeptide having the formula ##STR1## wherein R is H or OH and a method of producing is described. The agent has very high activity against human pathogens and is of very low mammalian toxicity.

REFERENCES:
patent: 4737487 (1988-04-01), Watts et al.
patent: 5021341 (1991-06-01), Giacobbe et al.
Kurokawa, et al., J. Am. Chem. Soc. 108: 6041-6043 (1986).
Cram, et al., Org. Chem. 2D Ed. McGraw Hill Pub. Co., pp. 607-613 (1964).

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