Antibiotic A82810

Details Antibiotic A82810 Antibiotic A82810

1993-04-02

1996-09-03

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 168, 536 172, 536 179, 536 181, 514 23, 514 27, A61K 3170, C07K 1704

Patent

active

055523862

ABSTRACT:
New polyether antibiotic A82810, its acyl and alkyl ester, acyl ester and urethane derivatives, and salts thereof, are useful antibacterial and anticoccidial agents and increase feed-utilization efficiency in animals. Methods of making A82810 by culture of Actinomodura fibrosa sp. nov. NRRL 18348 and synergistic compositions of the A82810 compounds with nicarbazin, 4,4'-dinitrocarbanilide, certain napthalenamine and benzenamine compounds and metichlorpindol are also provided.

REFERENCES:
patent: 4195079 (1980-03-01), Celmer et al.
patent: 4407946 (1983-10-01), Labeda et al.
patent: 4582822 (1986-04-01), Hamill et al.
patent: 4683204 (1987-07-01), Boeck
patent: 4746650 (1988-05-01), Cullen et al.
J. Tone, et al., "CP-47,433 and CP-47,434, New Polycyclic Ether Antibiotics Produced by a New Species of Actinomadura," Proc. 11th Intl. Congress of Chemotherapy and 19th ICAAC Meeting, Oct. 1979, pp. 469-470.
G. Nakamura et al., "A New Species of Actinomadura Producing a Polyether Antibiotic. Cationomycin," J. Antibiotics 36(11), 1468-1472 (1983).
Meiji Seika Kaisha, Derwent Abstract 87-002439/01 Abstracting Japan Kokai Tokkyo Koho J6 1260-888-A, "New Antibiotic SF-2361," Nov. 19, 1986.
Cullen et al., "CP-54,883 A Novel Chlorine-Containing Polyether Antibiotic Produced by a New Species of Actinomadura," J. Antibiotics 40(11) 1490-1495 (1987).
Meiji Seika Kaisha, Derwent Abstract No. 87-106351/15 and Chem. Abstract 107: 5760k of Japan Kokai Tokkyo Koho JP 62 55-090-A (Mar. 10, 1987).
Pfizer, Derwent Abstract 88-030532/05 of European Published Patent EP-255-335-A (Feb. 3, 1988).
Kusakabe et al., "Portmicin, A New Antibiotic," J. Antibiotics 40 (2), 237-238 (1987).

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