Antibiotic A80915 and process for its production

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435148, 435822, 435886, 549389, 514454, C12P 724, C12R 1465, C07D31192, A61K 3135

Patent

active

049045903

ABSTRACT:
New antibiotic A80915 and its dehydrochlorination derivatives are useful antibacterial agents. Methods of making antibiotic A80915 by culture of Streptomyces aculeolatus, NRRL 18422, and compositions containing an A80915 antibiotic also are provided.

REFERENCES:
patent: 4587218 (1986-05-01), Hershberger
patent: 4713331 (1987-12-01), Michel et al.
K. Shiomi et al., "Structures of New Antibiotics Napyradiomycins", The Journal of Antibiotics, vol. 39, No. 4, Apr. 1986, pp. 494-501.
K. Shiomi et al., "Novel Antibiotics Napyradiomycins Production, Isolation, Physico-Chemical Properties and Biological Activity", The Journal of Antibiotics, vol. 39, No. 4, Apr. 1986, pp. 487-493.
K. Shiomi et al., "New Antibiotic Napyradiomycins A2 and B4 and Stereochemistry of Napyradiomycins", The Journal of Antibiotics, vol. 40, No. 9, Sep. 1987, pp. 1213-1219.
S. Gomi et al., "Studies on New Antibiotics SF2415. II. The Structural Elucidation", The Journal of Antibiotics, vol. 40, No. 6, Jun. 1987, pp. 740-749.
T. Shomura et al., "Studies on New Antibiotics SF2415. I. Taxonomy, Fermentation, Isolation, Physico-Chemical Properties and Biological Activities", The Journal of Antibiotics, vol. 40, No. 6, Jun. 1987, pp. 732-739.

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