Antibiotic A53868 and process for production thereof

Details Antibiotic A53868 and process for production thereof Antibiotic A53868 and process for production thereof

1984-04-05

1984-11-13

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

044824882

ABSTRACT:
Antibiotic A53868 factor A, which is N.sup.2 -glycyl-N-(2-methylene-2-phosphonoethyl)leucinamide, and the formula: ##STR1## and the salts thereof, which are useful as antibiotics or as intermediates to antibiotics; methods of preparing A53868 factor A by fermentation of Streptomyces luridus; and the microorganism S. luridus NRRL 15101.

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K. Hemmi et al., "Studies on Phosphonic Acid Antibiotics, IV, Synthesis and Antibacterial Activity of Analogs of 3-(N-Acetyl-N-hydroxyamino)propylphosphonic Acid (FR-900098)", ibid, 30 (1), 111-118, (1982).

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