Antibiotic A201C, A201D and A201E

Harness for working animal

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424119, 536 4, 536 26, 542422, C07D40514

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active

042051649

ABSTRACT:
Antibiotics of the formula ##STR1## wherein R is .alpha.-3,4-di-O-methylrhamnosyl, are produced by the cultivation of Streptomyces capreolus NRRL 11429 under submerged aerobic fermentation conditions. A crude antibiotic mixture is obtained from the fermentation medium by extraction. The compounds of Formula II, III, and IV are separated from coproduced Antibiotic A201A (See U.S. Pat. No. 3,843,784) and from each other by repetitive chromatography on silica gel.

REFERENCES:
patent: 3843784 (1974-10-01), Hamill et al.
patent: 4087603 (1978-05-01), Hamill et al.
patent: 4143141 (1979-03-01), Ensminger
Kirst et al., Abstracts of 16th Interscience Conference on Antimicrobial Agents & Chemotherapy, Oct. 27-29, 1976, paper #61.

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