Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1991-07-17
1993-07-20
Chan, Y. Christina
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 11, 530317, 530323, 424117, 424118, 426635, 435 713, 435170, 435822, A61K 3702, A61K 3574, C07K 754, C12P 2100
Patent
active
052293629
ABSTRACT:
Newly-discovered antibiotic A10255 factors B, C, E, F, G, H, and J are produced by submerged aerobic fermentation of Streptomyces gardneri NRRL 15537 and NRRL 18260 or an A10255-producing variant or mutant thereof. The antibiotics are active against a wide variety of pathogenic bacteria, and also enhance feed-utilization efficiency in chickens, weanling pigs, cattle and sheep. The antibiotics can also be used to detect the thiostrepton-resistance gene in Streptomyces species.
REFERENCES:
patent: 3689639 (1972-09-01), Bergy et al.
patent: 4333923 (1982-06-01), Beck et al.
J. M. Liesch and K. L. Rinehart, "Berninamycin 3. Total Structure of Berninamycin A", J. Am. Chem. Soc., 99:5, Mar. 2, 1977.
Kirst Herbert A.
Michel Karl H.
Chan Y. Christina
Eli Lilly and Company
Fontana Steven A.
Harrison Nancy J.
Whitaker Leroy
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