Antibiotic A-7413 and process for preparation thereof

Details Antibiotic A-7413 and process for preparation thereof Antibiotic A-7413 and process for preparation thereof

1978-08-11

1979-11-13

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

424115, 435827, 435170, A61K 3500

Patent

active

041743903

ABSTRACT:
Antibiotic A-7413 complex, comprising a major microbiologically active factor A, and minor active factors B, C, and D, is produced by fermentation of Actinoplanes sp. NRRL 8122. The individual factors are isolated and separated by extraction and chromatography. The A-7413 antibiotics are antibacterial agents. The A-7413 complex and A-7413 antibiotic compounds are also useful as growth-promoting agents and in the control of dental caries and acne.

REFERENCES:
Miyaiui et al., J. Antibiotics 23(3), pp. 113-119, (1970).
Mizuno et al., J. Antibiotics 21(6), pp. 429-431, (1968).
Umezawa, Index of Antibiotics from Actinomycetes, University Park Press, State College, Penn., 1967, pp. 598, 634 & 654.
Derwent Abstract #59138w, Abstracting West German Pat. No. 2507--565.
Ebata et al., J. Antibiotics, 22, (10), pp. 451-456, (1969).

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