Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis
Patent
1978-08-18
1982-12-28
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
Having a known elemental analysis
424115, 435169, 435170, 435827, 435128, 435115, 435109, A61K 3500
Patent
active
043661475
ABSTRACT:
Antibiotic A-7413 complex, comprising a major microbiologically active factor A, and minor active factors B, C, and D, is produced by fermentation of Actinoplanes sp. NRRL 8122. The individual factors are isolated and separated by extraction and chromatography. The A-7413 antibiotics are antibacterial agents. The A-7413 complex and A-7413 antibiotic compounds are also useful as growth-promoting agents and in the control of dental caries and acne.
REFERENCES:
patent: 3642984 (1972-02-01), Bergy et al.
patent: 3697646 (1972-10-01), Coronelli et al.
patent: 3761587 (1973-09-01), Miyaili et al.
H. Umezawa, "Index of Antibiotics from Actinomycetes", University Park Press, State College, Penn., 1967, pp. 598, 634 and 654.
Miyairi et al., J. Antibiotics 23(3), pp. 113-119 (1970).
Mizuno et al., J. Antibiotics 21(6), pp. 429-431 (1968).
Derwent Abstract No. 59138w, Abstracting West German Pat. No. 2507-2565.
Hamill Robert L.
Stark W. Max
Eli Lilly and Company
Goldberg Jerome D.
Harrison Nancy J.
Whale Arthur R.
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