Antibiotic A-4696 factors B.sub.1, B.sub.2, B.sub.3, C.sub.1a, C

Details Antibiotic A-4696 factors B.sub.1, B.sub.2, B.sub.3, C.sub.1a, C Antibiotic A-4696 factors B.sub.1, B.sub.2, B.sub.3, C.sub.1a, C

1980-12-18

1982-03-30

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

424 49, A61K 3500, A61K 716

Patent

active

043224067

ABSTRACT:
Antibiotic A-4696 factors B.sub.1, B.sub.2, B.sub.3, C.sub.1a, C.sub.3, and E.sub.1 are isolated from antibiotic A-4696, the latter being produced by Actinoplanes missouriensis strains ATCC 31680, ATCC 31682, and ATCC 31683 under submerged aerobic conditions in a culture medium and isolated from the fermentation broth by absorption on an ion exchange resin and eluted therefrom at p.sup.H 10.5 with sodium hydroxide. The novel factors are separated by thin layer chromatography and high pressure liquid chromatography and have antimicrobial and growth promotant activity.

REFERENCES:
patent: 3952095 (1976-04-01), Hamill et al.
patent: 4064233 (1977-12-01), Hamill et al.
patent: 4115552 (1978-09-01), Hamill et al.

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