Antibiotic A-32390 and process for preparation thereof

Details Antibiotic A-32390 and process for preparation thereof Antibiotic A-32390 and process for preparation thereof

1976-02-19

1976-10-19

Monacell, A. Louis

Textiles: fiber preparation

C12D 900

Patent

active

039869288

ABSTRACT:
Antibiotic A-32390 complex, comprising factor A and other structurally related factors, is produced by cultivation of Pyrenochaeta sp. NRRL 5786 under submerged aerobic conditions, and isolated by extraction of the broth. Individual A-32390 factor A is separated by chromatography. The A-32390 complex, individual factor A and acyl ester derivatives of factor A inhibit dopamine-.beta.-hydroxylase and have antifungal, antibacterial, and hypotensive activity.

REFERENCES:
patent: 3932219 (1976-01-01), Michel et al.
Chemical Abstracts, vol. 65, 15,826 b, 1972.

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