Antibiotic 7-(thiazolyl)-3-(pyrazinylmethyl) or (pyridazinylmeth

Details Antibiotic 7-(thiazolyl)-3-(pyrazinylmethyl) or (pyridazinylmeth Antibiotic 7-(thiazolyl)-3-(pyrazinylmethyl) or (pyridazinylmeth

1983-11-16

1986-10-21

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540222, A61K 31545, C07D50146

Patent

active

046186069

ABSTRACT:
The invention relates to antibiotic compounds of the formula: ##STR1## wherein R.sup.1 represents a hydrogen atom or a carboxyl-protecting group; R.sup.2 represents a group of the formula: ##STR2## R.sup.3 represents a hydrogen atom or an alkoxy group; R.sup.4 represents a hydrogen atom or a halogen atom; R.sup.5 represents a hydrogen atom or a protected or unprotected amino group; A represents a group of the formula, --CH.sub.2 -- or a group of the formula, ##STR3## or a group of the formula, ##STR4## and the bond means that the compound may be a synisomer or an anti-isomer or a mixture thereof.

REFERENCES:
patent: 4293550 (1981-10-01), Blumbach
patent: 4366153 (1982-12-01), Takaya
Green, "Protective Groups in Organic Synthesis", (1981), pp. 10, 11, 13, 14 and 15.
Takeda, Derwent Abstract, 65150.
Dunn, Journal of Antimicrobial Chemotherapy, (1982) 10, Suppl. C., 1-10.

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