Antibiotic 67-121, a polyene antifungal antibiotic produced by A

Details Antibiotic 67-121, a polyene antifungal antibiotic produced by A Antibiotic 67-121, a polyene antifungal antibiotic produced by A

1978-09-28

1980-09-16

Goldberg, Jerome D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424119, 424181, C07H 1708, A61K 3171

Patent

active

042231302

ABSTRACT:
A microorganism of the genus Actinoplanes produces a novel complex of polyene antibiotics herein designated collectively Antibiotic 67-121 (and sometimes referred to as the Antibiotic 67-121 complex). The individual components are designated Antibiotic 67-121A, Antibiotic 67-121B, Antibiotic 67-121C and Antibiotic 67-121D. The individual components have ultraviolet spectra characteristic of heptaenes. Further, they are orally active against a variety of strains of Candida albicans including many clinical isolates thereof.

REFERENCES:
patent: 3700768 (1972-10-01), Kunstmann et al.

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