Antibiotic 5-lipoxygenase inhibitors

Details Antibiotic 5-lipoxygenase inhibitors Antibiotic 5-lipoxygenase inhibitors

1992-06-25

1993-05-04

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

435183, 4352535, 435 41, C07C22900

Patent

active

052083640

ABSTRACT:
Novel compounds derived from cultures of Streptomyces sp. AA2807 are useful as 5-lipoxygenase inhibitors.

REFERENCES:
patent: 4861798 (1989-08-01), Tramposch et al.
Elsevier et al, "Haemodynamics, Hormones and Inflammations", Discoveries in Pharmacology, vol. 2, (1984), pp. 523-553.
Taylor et al, Trends Pharmacal. Sci, vol. 7, (1986), p. 100.
Sirois, Adv. Lipid Res. vol. 21, (1985), p. 79.
Dahlen et al, "Nature", vol. 288, (1980), p. 484.
Ford-Hutchinson, "J. R. Soc. Med," vol. 74, (1981), p. 831.
Camp et al, "Prostaglandins", vol. 26, (1983), p. 432.
Cashman, J. R. "Pharm. Res.", (1985), p. 253.
Kitamura et al, "Novel Microbial Products for Medicine and Agriculture", Society for Industrial Microbiology, Chapter 17, (1989), pp. 145-150.
Tramposch et al, "Biochemical and pharmacological properties of a new topical antiinflammatory compound, 9-phenylnonano-hydroxamic acid", Agents and Actions, vol. 30, (1990), p. 443.

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