Antibacterially active hexamethylene-bis-biguanides

Details Antibacterially active hexamethylene-bis-biguanides Antibacterially active hexamethylene-bis-biguanides

1975-05-01

1977-05-10

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603437, 260239BA, 26050114, 424280, 424316, 424326, C07C12916

Patent

active

040228347

ABSTRACT:
There are disclosed new hexamethylene-bis-biguanides having antibacterial activity, and two processes for the preparation thereof. The new compounds have the general formula ##STR1## wherein R represents H, and R' represents an hexyl or pentyl group being substituted with one or two methyl groups, or represents a cycloalkyl group having more than 6 carbon atoms, a lower-alkyl-cycloalkyl group or a cycloalkyl-lower-alkyl group, or R and R' together with the adjacent nitrogen atom represent an azabicyclo(3,2,2)-nonane double ring.

REFERENCES:
patent: 3468898 (1969-09-01), Cutler et al.
Rose et al., J. Chem. Soc. (London) 1956 pp. 4422-4425.

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