Antibacterial substance

Details Antibacterial substance Antibacterial substance

1989-11-06

1991-07-23

Doll, John

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

15 to 23 amino acid residues in defined sequence

530324, 530325, C07K 708, C07K 710

Patent

active

050345109

ABSTRACT:
An antibacterial substance comprising a peptide comprising a fragment constituting lepidopteran A and containing the N-terminal amino acid residue of the lepidopteran A, wherein the carboxyl group at the C-terminal of said peptide is substituted with an alkyl amide group represented by Formula (I):

REFERENCES:
patent: 3720690 (1973-03-01), King et al.
patent: 4350627 (1982-09-01), Castiglione et al.
Merrifield et al., Biol. Abstr. 76(10)-70382 (11/3/83).
Shiba et al., Chem. Abstr. vol. 101, No. 53121a (1984).
Andreu et al., Chem. Abstr. vol. 103, No. 123890t (1985).
Van Hopstem et al., Biol. Abstr. 80(4): 32029 (8/15/85).
Nakai et al., Peptide Chemistry pp. 207-212 (1985).
Shiba et al., Walter de Gruyter & Co., Berlin New York (1987 published).
E. Wunsch: "Synthese von Peptiden," in Houben-Weyl, Methoden der Organischen Chemie, edition 4, vol. XV/1, 1974, pp. 6-7, Georg Thieme Verlag, Stuttgart, DE.

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