Antibacterial solution

Details Antibacterial solution Antibacterial solution

2001-06-05

2002-11-12

Page, Thurman K. (Department: 1615)

Drug, bio-affecting and body treating compositions

Topical body preparation containing solid synthetic organic...

Skin cosmetic coating

C424S405000, C424S400000

Reexamination Certificate

active

06479044

ABSTRACT:

FIELD OF THE INVENTION
The present invention relates to an aqueous antibacterial solution containing an anionic surfactant, a polycationic antibacterial agent and water, wherein the antibacterial solution has improved substantivity onto surfaces for a lasting protection against bacteria.
BACKGROUND OF THE INVENTION
Poly (hexamethylene biguanide) hydrochloride has been used in the food industry as an antibacterial solution for equipment disinfection but these solutions exhibit poor substantivity in that once the bacteria has been killed on the initial treatment with the antibacterial solution, new bacteria can readily grow on the treated surface. The instant aqueous antibacterial solution of a complex of an anionic surfactant and a poly (hexamethylene biguanide) hydrochloride exhibits improved substantivity in that the treated surface is resistant to the growth of new bacteria.
Poly (hexamethylene biguanide) hydrochloride has been used in combination with a cationic surfactant such as didecyl dimethyl ammonium chloride in laundry compositions but the substantivity of these laundry compositions is inferior.
Patent applications WO99/40791 and EPO891712A1 comprises a substantive antibacterial solution containing silver ions, poly (hexamethylene biguanide) hydrochloride which is crosslinked by sodium lauryl sulfate.
Avecia Limited of England also provides poly (hexamethylene biguanide) stearate for soap bars.
SUMMARY OF THE INVENTION
The present invention relates to an aqueous antibacterial solution having improved substantivity which comprises a complex of an anionic surfactant and poly (hexamethylene biguanide) hydrochloride in suspension in water.
An objective of the present invention is to provide an antibacterial solution for the treatment of a surface containing bacteria, wherein the treated surface is resistant to further growth of new bacteria.
DETAILED DESCRIPTION OF THE INVENTION
The present invention relates to an aqueous antibacterial solution which comprises approximately by weight:
(a) a complex of 0.01% to 5.0%, more preferably 0.1% to 0.5% of an anionic surfactant and 0.01% to 2%, more preferably 0.04% to 0.2% of a cationic polymer selected from the group consisting of poly (hexamethylene biguanide) hydrochloride having the structure of:
where the average n=4 to 6 and a quaternized cationic polymer having the structure of
(b) 0 to 1%, more preferably 0.01% to 1.0% of an ethoxylated nonionic surfactant;
(c) 0 to 1%, more preferably 0.01% to 1.0% of an emulsifier;
(d) 0 to 0.75%, more preferably 0.05% to 0.4% of a fragrance or essential oil;
(e) the balance being water, wherein the composition does not contain silver ions, anionic surfactant as crosslinking agent, poly (hexamethylene biguanide) stearate or a cationic surfactant such as a quaternary ammonium compound.
As used herein and in the appended claims the term “perfume” is used in its ordinary sense to refer to and include any non-water soluble fragrant substance or mixture of substances including natural (i.e., obtained by extraction of flower, herb, blossom or plant), artificial (i.e., mixture of natural oils or oil constituents) and synthetically produced substance) odoriferous substances. Typically, perfumes are complex mixtures of blends of various organic compounds such as alcohols, aldehydes, ethers, aromatic compounds and varying amounts of essential oils (e.g., terpenes) such as from 0% to 80%, usually from 10% to 70% by weight, the essential oils themselves being volatile odoriferous compounds and also serving to dissolve the other components of the perfume.
Suitable essential oils are selected from the group consisting of: Anethole 20/21 natural, Aniseed oil china star, Aniseed oil globe brand, Balsam (Peru), Basil oil (India), Black pepper oil, Black pepper oleoresin 40/20, Bois de Rose (Brazil) FOB, Borneol Flakes (China), Camphor oil, White, Camphor powder synthetic technical, Cananga oil (Java), Cardamom oil, Cassia oil (China), Cedarwood oil (China) BP, Cinnamon bark oil, Cinnamon leaf oil, Citronella oil, Clove bud oil, Clove leaf, Coriander (Russia), Coumarin 69° C. (China), Cyclamen Aldehyde, Diphenyl oxide, Ethyl vanilin, Eucalyptol, Eucalyptus oil, Eucalyptus citriodora, Fennel oil, Geranium oil, Ginger oil, Ginger oleoresin (India), White grapefruit oil, Guaiacwood oil, Gurjun balsam, Heliotropin, Isobornyl acetate, Isolongifolene, Juniper berry oil, L-methyl acetate, Lavender oil, Lemon oil, Lemongrass oil, Lime oil distilled, Litsea Cubeba oil, Longifolene, Menthol crystals, Methyl cedryl ketone, Methyl chavicol, Methyl salicylate, Musk ambrette, Musk ketone, Musk xylol, Nutmeg oil, Orange oil, Patchouli oil, Peppermint oil, Phenyl ethyl alcohol, Pimento berry oil, Pimento leaf oil, Rosalin, Sandalwood oil, Sandenol, Sage oil, Clary sage, Sassafras oil, Spearmint oil, Spike lavender, Tagetes, Tea tree oil, Vanilin, Vetyver oil (Java), Wintergreen, Allocimene, Arbanex™, Arbanol®, Bergamot oils, Camphene, Alpha-Campholenic aldehyde, I-Carvone, Cineoles, Citral, Citronellol Terpenes, Alpha-Citronellol, Citronellyl Acetate, Citronellyl Nitrile, Para-Cymene, Dihydroanethole, Dihydrocarveol, d-Dihydrocarvone, Dihydrolinalool, Dihydromyrcene, Dihydromyrcenol, Dihydromyrcenyl Acetate, Dihydroterpineol, Dimethyloctanal, Dimethyloctanol, Dimethyloctanyl Acetate, Estragole, Ethyl-2 Methylbutyrate, Fenchol, Fernlol™, Florilys™, Geraniol, Geranyl Acetate, Geranyl Nitrile, Glidmint™ Mint oils, Glidox™, Grapefruit oils, trans-2-Hexenal, trans-2-Hexenol, cis-3-Hexenyl Isovalerate, cis-3-Hexanyl-2-methylbutyrate, Hexyl Isovalerate, Hexyl-2-methylbutyrate, Hydroxycitronellal, lonone, Isobornyl Methylether, Linalool, Linalool Oxide, Linalyl Acetate, Menthane Hydroperoxide, I-Methyl Acetate, Methyl Hexyl Ether, Methyl-2-methylbutyrate, 2-Methylbutyl Isovalerate, Myrcene, Nerol, Neryl Acetate, 3-Octanol, 3-Octyl Acetate, Phenyl Ethyl-2-methylbutyrate, Petitgrain oil, cis-Pinane, Pinane Hydroperoxide, Pinanol, Pine Ester, Pine Needle oils, Pine oil, alpha-Pinene, beta-Pinene, alpha-Pinene Oxide, Plinol, Plinyl Acetate, Pseudo lonone, Rhodinol, Rhodinyl Acetate, Spice oils, alpha-Terpinene, gamma-Terpinene, Terpinene-4-OL, Terpineol, Terpinolene, Terpinyl Acetate, Tetrahydrolinalool, Tetrahydrolinalyl Acetate, Tetrahydromyrcenol, Tetralol®, Tomato oils, Vitalizair, Zestoral™, HINOKITIOL™ and THUJOPSIS DOLABRATA™.
In the present invention the precise composition of the perfume is of no particular consequence to cleaning performance so long as it meets the criteria of water immiscibility and having a pleasing odor. Naturally, of course, especially for cleaning compositions intended for use in the home, the perfume, as well as all other ingredients, should be cosmetically acceptable, i.e., non-toxic, hypoallergenic, etc.
The water soluble nonionic surfactants utilized in this invention are commercially well known and include the primary aliphatic alcohol ethoxylates, secondary aliphatic alcohol ethoxylates, alkylphenol ethoxylates and ethylene-oxide-propylene oxide condensates on primary alkanols, such a Plurafacs (BASF) and condensates of ethylene oxide with sorbitan fatty acid esters such as the Tweens (ICI). The nonionic synthetic organic detergents generally are the condensation products of an organic aliphatic or alkyl aromatic hydrophobic compound and hydrophilic ethylene oxide groups. Practically any hydrophobic compound having a carboxy, hydroxy, amido, or amino group with a free hydrogen attached to the nitrogen can be condensed with ethylene oxide or with the polyhydration product thereof, polyethylene glycol, to form a water-soluble nonionic detergent. Further, the length of the polyethenoxy chain can be adjusted to achieve the desired balance between the hydrophobic and hydrophilic elements.
The nonionic surfactant class includes the condensation products of a higher alcohol (e.g., an alkanol containing about 8 to 18 carbon atoms in a straight or branched chain configuration) condensed with about 5 to 30 moles of ethylene oxide, for example, lauryl or myristyl alcohol condensed with about 16

Affiliated with

Also associated with

Rating

Antibacterial solution does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibacterial solution, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibacterial solution will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2945615