Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-08-16
2011-08-16
Padmanabhan, Sreeni (Department: 1627)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S157000
Reexamination Certificate
active
07998979
ABSTRACT:
The present invention relates to novel substituted quinoline derivatives according to the general formula (Ia) or formula (Ib):including any stereochemically isomeric form thereof, a pharmaceutically acceptable salt thereof, a N-oxide form thereof or a solvate thereof. The claimed compounds are useful for the treatment of a bacterial infection. Also claimed is a composition comprising a pharmaceutically acceptable carrier and, as active ingredient, a therapeutically effective amount of the claimed compounds, the use of the claimed compounds or compositions for the manufacture of a medicament for the treatment of a bacterial infection and a process for preparing the claimed compounds.
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Andries, K., et al. “A Diaryiquinotine Drug Active on the ATP Synthase of Mycobacterium Tuberculosis”, Science (Washington D.C.), vol. 307, No. 5707, pp. 223-227 (2005).
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Andries Koenraad Jozef Lodewijk Marcel
Guillemont Jérôme Emile Georges
Koul Anil
Motte Magali Madeleine Simone
Dodd Thomas J.
Janssen Pharmaceutical N.V.
Javanmard Sahar
Padmanabhan Sreeni
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